What is HINT

HINT (High-quality INTeractomes) is a curated compilation of high-quality protein-protein interactions from 8 interactome resources (BioGRID, MINT, iRefWeb, DIP, IntAct, HPRD, MIPS and the PDB). Interactions are filtered both systematically and manually to remove erroneous and low-quality interactions, and is updated every night. HINT can be used for individual queries as well as for batch downloads.

HINT dataset has been updated in Februrary, 2024. We are in the process of building another new HINT website. The most recent dataset is in "2023_10" folder in "Download old versions".